生物识别元件功能化微纳米磁性材料在真菌毒素检测中的应用

Application of Biological Recognition Element-Based Functional Magnetic Micro/Nano-Material in Mycotoxin Determination

真菌毒素是真菌产生的一类强毒性次级代谢产物,可通过食品或食物链危害人类的健康。建立快速、准确、灵敏的检测方法是控制真菌毒素危害的有效手段之一。功能化微纳米磁性材料因具有超顺磁性、比表面积大等特性,近年来在建立样品前处理新方法及生物传感器分析等领域的应用日益增多。本文在概述真菌毒素传统检测方法及微纳米磁性材料特点的基础上,综述近期生物识别元件功能化微纳米磁性材料在样品前处理及利用生物传感器高灵敏快速检测真菌毒素中的应用,并对其发展进行展望。

Mycotoxins are small secondary metabolites with high toxicity produced by a few fungal species. They are harmful to human and animal health by contaminating food and entering the food chain. One of the effective approaches for controlling mycotoxin hazard is to develop rapid, accurate and sensitive analytical methods. Recently, the functionalized magnetic materials have been widely applied in sample pretreatment and biosensor detection due to their good characteristics such as superparamagnetization and high specific surface area. In this review the traditional mycotoxin detection methods and the merits of magnetic materials are summarized. The emerging sample pretreatment methods and biosensor detection methods involving magnetic nano-materials for mycotoxin determination are discussed in detail, and future research trends are proposed.