复凝聚法制备2-苯乙醇微胶囊及稳定性研究

Preparation and Stability of Microcapsules of 2-Phenylethanol by Complex Coagulation Method

以羧甲基壳聚糖(carboxymethyl chitosan,CMC)、海藻酸钠(sodium alginate,SA)为壁材,采用复凝聚法制备2-苯乙醇微胶囊。考察壁材用量对微胶囊中2-苯乙醇含量的影响,以确定微胶囊最佳制备条件。测试微胶囊在不同温度下对2-苯乙醇快速释放情况,以及微胶囊在长期贮藏中吸水量、表面形貌及缓释性能变化情况。通过最佳制备条件制备的微胶囊中包埋2-苯乙醇的含量最高,为1.42%。通过以CoCl_2作指示剂,在相同条件下制备CoCl_2微胶囊,能直观准确的考察微胶囊的吸水量与颜色变化之间的定量关系。CoCl_2微胶囊在贮藏过程颜色中随着吸水量的逐渐增加由蓝色转变为红色,其吸水量与颜色变化之间存在二次函数曲线关系。

Microcapsules of 2-phenylethanol were prepared through complex coacervation method,using carboxymethyl chitosan(CMC)and sodium alginate(SA)as the wall materials.The effects of amounts of CMC and SA on the content of 2-phenylethanol were investigated to determine the optimum preparation conditions.The rapid released of 2-phenylethanol from microcapsules at different temperatures and the changed of water absorption,surface morphology and sustained released properties of microcapsules during long-term storage were measured.The highest content of 2-phenylethanol was 1.42%in the microcapsules prepared under the optimum preparation conditions.Using CoCl2 as an indicator,microcapsules of CoCl2 were prepared under the same conditions and used to visually and accurately investigate the quantitative relationship between water absorption and color change of microcapsules.The color of microcapsules of CoCl2 changed from blue to red as the water absorption increased during storage.The relationship between water absorption and color change was quadratic curve relationship.