川秋葵微粉降血糖活性研究

Study on the Hypoglycemic Activity of Sichuan Okra Micropowder

热风干燥制备川秋葵微粉,研究川秋葵微粉在体内和体外的降血糖活性。结果表明:川秋葵微粉具有良好的体外降血糖活性,阿卡波糖对α-葡萄糖苷酶抑制活性优于秋葵微粉,但差异不显著(P> 0.05);阿卡波糖对α-淀粉酶活性抑制活性优于秋葵微粉,差异不显著(P> 0.05);当葡萄糖溶液浓度为50 mmol/L时,秋葵微粉对葡萄糖吸附能力最强(P <0.01),为(397.08±0.64)mg/g;秋葵微粉对葡萄糖透析延迟指数随透析时间延长先增加后降低(P <0.05),60 min达到最高值(49.63±4.45)%。根据国际认可的Wolever和Salmeron公式分别计算得到秋葵微粉的血糖生成指数(glycemic index,GI)为40.8,血糖负荷(glycemic load,GL)为9.1,均为低GI低GL食品;相较于葡萄糖粉血糖应答曲线的速升速降,秋葵微粉的血糖应答曲线均呈缓升缓降趋势,曲线波动小,有利于机体餐后血糖的稳定。

In order to study the hypoglycemic activity of Sichuan okra micropowder in vitro and in vivo,the dry powder of okra was prepared by hot air drying.The results showed that the micropowder of okra had good in vitro hypoglycemic activity,and the inhibitory activity of acarbose onα-glucosidase was better than that of okra micropowder,but the difference was not significant(P>0.05).The inhibitory activity of acarbose onα-amylase was better than that of okra powder,but the difference was not significant(P>0.05).When the concentration of glucose solution was 50 mmol/L,the glucose adsorption ability of okra powder was the strongest(P<0.01),which was(397.08±0.64)mg/g.The glucose dialysis delay index of okra powder increased with dialysis duration(P<0.05),and the highest value of 60 min reached(49.63±4.45)%.According to the internationally recognizedWolever and Salmeron formulas,the glycemic index(GI)value of the okra powder was calculated 40.8,and the glycemic load(GL)value was 9.1.All of them were low GI and low GL food.Compared with the rapid rise and speed drop of glucose response curve of glucose powder,the blood glucose response curve of the micropowder of okra was slowly rising and decreasing,and the curve fluctuated slightly,which was beneficial to the stability of postprandial blood glucose.