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Tamoxifen Injection induce transient myocardiac dysfunction in mice

Tamoxifen Injection induce transient myocardiac dysfunction in mice
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摘要 Tamoxifen inducible cre-loxp system has been employed as a very powerful tool for cardiology research in mice. It enables researchers to control their interested gene expression in tight control in terms of tissue specification and time specification. Here, we reported that in the absence of loxp transgenes,tamoxifen injection can lead to myocardiac dysfunction 3 days after drug administration but cardiac function start recover from 2 days later. Tamoxifen inducible cre-loxp system has been employed as a very powerful tool for cardiology research in mice. It enables researchers to control their interested gene expression in tight control in terms of tissue specification and time specification. Here, we reported that in the absence of loxp transgenes,tamoxifen injection can lead to myocardiac dysfunction 3 days after drug administration but cardiac function start recover from 2 days later.
出处 《生物技术世界》 2014年第3期99-101,共3页 Biotech World
关键词 TAMOXIFEN CARDIOLOGY ECHO Tamoxifen Cardiology echo
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参考文献8

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