肺炎链球菌血清学分型的研究

Serological Typing among 712 Clinical Isolates of Streptococcus Pneumoniae

用荚膜肿胀试验方法,对我国分离的712株肺炎链球菌进行分型研究的结果表明:712株肺炎链球菌共分成42个型(群),未发现40、42、44和4 7.型(群)。在常见的血清型(群)中,以5型最多,其次是6、1、19、2、14、23和3型(群),以上8个型(群)共453株,占63.6%。另外还发现16A 和10C 型新型菌株。从脑脊髓液(CSF)分离出180株肺炎链球菌是2型最多,其次是5、6、1、27、23、14、12和7型(群),以上9个型共137株,占76.1%。从血液中分离出71株肺炎链球菌,以1型最常见,其次是5、6、14、19、7、8和35型(群),以上8个型(群)共52株,占72.6%。从中耳液中分离出253株肺炎链球菌,其中19群占首位,其次是6、5、23、14、3、1和15型(群),以上8个型(群)共183株,占72.3%。

712 clinical isolates of S pneumoniae was serogrouped into 42 groups or Lypes by“quel- lung”reaction with lyping sera among which types 40,42,44 and 47 had not been found in Chlna before.of the 712 strains,type(group)5,6,1,19,23,2,14 and 3 were the most frequently encountered ones and these eight types(groups)totaled 453 strains(63.3%)and type 16A and 10C are found as new types. of the 180 isolates ftom CSF,137 strains(76.1%)of type(group)2,5,6,1,27,23,14,12 and 7 were the common estones;52 of 71 strains from blood(72.6%)the most common types(groups) were 1,5,6,14,19,7,8 and 35,183 of 253 strains(72.3%)isolated from otitis fluids.The most common types(groups)were 19,6,5,23,14,3,1 and 15.