每日唤醒干预模式对机械通气镇静治疗病人临床效果及不良事件的影响

Influence of daily wake-up intervention model on clinical effect and adverse events in patients with mechanical ventilation and sedation therapy

[目的]探讨每日唤醒干预模式对机械通气镇静治疗的危重病人临床效果及不良事件的影响。[方法]选取我院重症监护病房(ICU)2013年9月—2015年7月收治的84例机械通气镇静治疗的危重病人,随机分为研究组和对照组各42例。对照组实施常规护理干预,研究组在对照组基础上引入每日唤醒干预。比较两组病人丙泊酚、咪达唑仑的使用总剂量、平均剂量、机械通气时间、ICU治疗时间及不良事件发生率。[结果]研究组丙泊酚平均使用剂量、咪达唑仑使用总剂量及其平均使用剂量均少于对照组,差异有统计学意义(P<0.05);研究组病人机械通气时间及ICU治疗时间均短于对照组,差异有统计学意义(P<0.05);两组不良事件发生率比较差异无统计学意义(P>0.05)。[结论]每日唤醒干预有助于机械通气镇静治疗病人病情向着正性方向转归。

Objective:To probe into the influence of daily wake-up intervention model on clinical effect and adverse events in patients with mechanical ventilation and sedation therapy.Methods:A total of 84 critically ill patients who received mechanical ventilation and sedation therapy in intensive care unit(ICU)in our hospital were randomly divided into study group and control group respectively 42 cases in each from September 2013 to July2015.The patients in control group were given routine nursing intervention,the patients in study group were added daily wake-up intervention,then to compare with the total dose,average dose of propofol,midazolam,mechanical ventilation time,ICU treatment time and adverse event incidence in the two group.Results:Average dose of propofol and total and average dose of midazolam in study group were less than that in control group there was statistically significant difference between both groups(P<0.05);mechanical ventilation time,ICU treatment time in study group were shorter than that in control group,and there was statistically significant difference between both groups(P<0.05);there was no statistically significant difference in adverse events between both groups(P>0.05).Conclusion:The daily wake-up intervention was helpful for the treatment of patients with mechanical ventilation and sedation therapy in a positive direction.