认知障碍老年人握力和步速与认知功能的关系

Relationship between grip strength and pace speed and cognitive function in elderly patients with cognitive impairment

[目的]探讨认知障碍老年人握力和步速与认知功能的关系,为认知障碍的评估与预防提供参考。[方法]选择认知障碍老年人336例,根据认知障碍程度将老年人划分为轻度认知障碍组、中度认知障碍组和重度认知障碍组,另选134名体检的老年人为对照组。所有受试者填写一般情况调查表,接受简易精神状态量表测验及握力与步速测量。[结果]有效回收问卷470份(94.8%)。与对照组比较,轻度认知障碍组握力和步速值变化较小(P>0.05),中重度认知障碍组握力与步速值均明显下降(P<0.05);与轻度认知障碍组比较,中重度认知障碍组握力和重度组步速均明显下降(P<0.05);与中度认知障碍组比较,重度认知障碍组握力与步速明显下降(P<0.05)。握力与步速均与认知总得分、定向力与语言能力得分呈正相关(P<0.01),握力与视觉空间能力呈正相关(r=0.154,P<0.05)。[结论]握力和步速同时与中重度认知障碍老年人整体认知功能、定向力和语言能力呈正相关关系,二者降低可能提示认知障碍加深。

Objective:To probe into the relationship between grip strength and pace speed and cognitive function in elderly patients with cognitive impairment(CI),and to provide the reference for the evaluation and prevention of CI.Methods:A total of 336 elderly patients with CI were selected and divided into mild CI group,moderate CI group,and severe CI group according to the CI degree.The other 134 elderly patients were selected as the control group.All the patients conducted the survey by using the general questionnaire,Mini-Mental State Examination(MMSE),and grip strength and pace speed measurement.Results:A total of 470 questionnaires were recalled effectively(94.8%).Compared with the normal cognitive group,the changes of mild CI group in grip strength and pace speed were small(P>0.05),and the grip strength and pace speed in the moderate CI group were significantly decreased(P<0.05).Compared with the mild CI group,the grip strength and pace speed in the moderate CI group and severe CI group decreased significantly(P<0.05).Compared with the moderate CI group,the grip strength and pace speed in the severe CI group decreased significantly(P<0.05).Both grip strength and pace speed were positively correlated with the total cognitive score,orientation,and language ability scores(P<0.01),and grip strength was positively correlated with the visual spatial ability(r=0.154,P<0.05).Conclusions:Grip strength and pace speed were positively correlated with the overall cognitive function,the orientation,and language ability in the specific cognitive dimension of the elderly with moderate to severe CI.The reduction of the two factors may be a sign of deepening CI.