抗-E合并抗-Wra抗体鉴定

Detection of anti-E and anti-Wra antibodies

目的:探讨抗-Wra抗体的鉴定过程及该抗体潜在的临床意义。方法:对1例不规则抗体检测阳性男性骨髓增生异常综合征患者进行抗体特异性鉴定。盐水法、凝聚胺法以及抗人球法进行交叉配血试验。结果:患者血清中检出抗-E及抗-Wra抗体,E抗原阴性的血液与患者进行交叉配血,3种交叉配血法均相合。结论:输血后患者无任何不良输血反应。对anti-Wra抗体及其他低频抗体进行检测有利于了解其临床意义。

Objective:To describe the process of detection of anti-Wra antibody and the potential clinical risk of missing it.Method:One male patient diagnosed MDS with positive antibody screening was identified with Panel cells.Crossmatching that include saline test,polybrene test and antiglobulin test(AGT)were used to get compatible blood.Result:Anti-E and anti-Wra antibodies were identified in the person’s serum.Compatibility blood without E antigen was chosen to transfuse.No adverse transfusion reactions occurred.Conclusion:It’s essential to study the clinical significance of anti-Wra and other low incidence antibodies on our Chinese people.