摘要
1967年Macvie和Renton等同时报道了一个新发现的抗原Sda。首先是从先证者Sidney Smith血浆中发现了抗Sda,然后证明了这是一个新的抗原。原名使用是先证者名字缩写,ISBT命名为Sda,编号901012,属于系列抗原中的高频抗原。Sda抗原就是原来的多凝聚红细胞Cad抗原。
Sd^a antigen is a high frequency antigen(901012)in the'series'of antigens,and is a red blood cell antigen associated with GPA/GPB.Sd^a antigen belongs to glycan chain antigen.It is not only expressed on erythrocyte membrane,but also on tissue and cell.It exists in urine in a free state.The free Sd^a antigen in urine is expressed on Tamm-Horsfall protein.At present,this antigen has met the requirements of a'system'antigen and is likely to become the next system antigen.
出处
《临床血液学杂志（输血与检验）》
CAS
2019年第4期648-650,共3页
Journal of Clinical Hematology(Blood Transfusion & Laboratory Medicine)
