肿瘤相关静脉血栓栓塞症预防和治疗的现状与挑战

The present situation and challenge of the prevention and treatment of tumor related venous thromboembolism

静脉血栓栓塞症是肿瘤患者死亡的第二大原因。尽管出版了预防和治疗肿瘤相关静脉血栓栓塞症的共识及指南,但这些共识及指南和临床实践之间仍存在差距,且某些方面仍存在争议。肿瘤相关静脉血栓栓塞症的病理生理机制仍未被阐明,在这种情况下如何实施最佳抗凝预防和治疗对临床医生来说是一个重大挑战。

Venous thromboembolism is the second leading cause of death in tumor patients. Although the publication of major consensus guidelines setting out recommendations for thromboprophylaxis in tumor patients,It remains a gulf between these guidelines and clinical practice,and certain areas of controversy still remain. The pathophysiological mechanism of tumor related venous thromboembolism remains to be illuminated. Optimal anticoagulation in such instances presents a major challenge to clinicians.