不同检测方法诊断乳腺癌病灶的敏感性及其价值

Diagnostic Value of Different Detection Methods on Breast Cancer

目的比较不同检测方法在乳腺癌诊断中的应用效果。方法对60例疑似乳腺癌的患者在术前采用不同方法进行检查,并将结果与术后的病理结果相对比。结果病理检查诊断乳腺癌56例,余4例为乳腺良性肿块。X线、US、CT、MRI检查分别确诊乳腺癌40例、48例、49例、50例,其敏感度分别为71.4%、85.7%、87.5%、89.3%。特异度分别为50.0%、75.0%、75.0%、75.0%,阳性预测值分别为95.2%、98.0%、98.0%、98.0%,阴性预测值分别为11.1%、27.3%、30.0%、33.3%。US、CT、MRI诊断乳腺癌的敏感性、ROC线下面积与X线钼靶相比,P<0.05;但特异性、阳性预测值、阴性预测值相比,P均>0.05。结论与X线钼靶相比,US、CT、MRI诊断乳腺癌有较高的敏感性。

Objective To investigate the clinical value of different detection methods in the diagnosis of breast cancer.Methods 60 suspected breast cancer patients were examined by different detection methods before surgery. The results by different detection methods were compared with the patholigical examination after surgery. Results There were 56 breast cancer patients and 4 benign breast tumor patients diagnosed by patholigical examination. Breast cancer confirmed by X-ray,US,CT,and MRI examination were 40 cases,48 cases,49 cases,and 50 cases,respectively; Specificity were 50. 0%,75. 0%,75. 0%,and75. 0%,positive predictive value were 95. 2%,98. 0%,98. 0%,and 98. 0%,negative predictive value were 11. 1%,27. 3%,30. 0%,and 33. 3%. sensitivity and area under ROC curve of US、CT、MRI were higher than those of X-ray,P < 0. 05; specificity,positive and negative predictive value had no statistical difference( P > 0. 05). Conclusion Compared with X-ray,US,CT and MRI are more sensitive in the diagnosis of breast cancer.