中西医结合治疗直肠癌术后肠麻痹的临床效果观察

Clinical Observation of Integrated Traditional Chinese and Western Medicine in the Treatment of Postoperative Intestinal Paralysis of Rectal Carcinoma

目的探讨中西医结合治疗直肠癌术后肠麻痹的临床效果。方法选取经切除术治疗后出现肠麻痹的直肠癌患者60例,按照完全随机法1∶1分成2组,30例对照组患者行西医常规治疗,30例研究组患者在对照组基础上加用针灸、敷脐联合自拟保留灌肠汤,比较2组患者治疗后的疗效性指标与生化指标情况。结果研究组的肠鸣音、排便和排气恢复时间、腹胀消失、胃肠减压解除与留院观察时间均比对照组短,差异有统计学意义(P<0.05);研究组治疗24 h、72 h的中医征候积分分别为(10.26±3.27)分、(0.82±0.05)分,均比对照组(13.45±1.67、1.95±0.43)低,差异有统计学意义(P<0.05);研究组治疗后的K+水平(mmol/L)比对照组高(3.79±0.41 vs 3.51±0.39),TNF-α(μg/L)、CRP(mg/L)均比对照组低(1.05±0.24 vs 1.98±0.15,10.18±4.36 vs 24.36±7.23),差异均有统计学意义(P<0.05)。结论中西医结合治疗直肠癌术后麻痹,能够有效缓解患者病症,改善肠胃道功能,防止肠胃功能衰竭。

Objective To observe and analyze the clinical efficacy of integrated traditional Chinese and western medicine in the treatment of postoperative intestinal paralysis of rectal carcinoma. Methods 60 patients with rectal cancer after resection with intestinal paralysis were randomly divided into 2 groups,30 cases in the control group underwent routine treatment,30 cases in the study group received acupuncture combined with own reserves and umbilical enema decoction,based on the the control group,curative effects and biochemical indexes of the 2 groups were compared after treatment. Results The bowel sounds,defecation and exhaust recovery time,abdominal distention disappearing,gastrointestinal decompression,and hospital stay in the observation group were shorter than those of the control group,there had statistical difference( P < 0. 05); 24 h,72 h traditional Chinese medicine syndrome integral in the observation group were( 10. 26 ± 3. 27) and( 0. 82 ± 0. 05),which were lower than( 13. 45 ± 1. 67) and( 1. 95 ± 0. 43) of the control group,there had statistical difference( P < 0. 05); after treatment,the levels of K+( mmol/L) of the study group was higher than that of the control group( 3. 79 ± 0. 41 vs 3. 51 ± 0. 39),TNF-alpha( μg/L),CRP( mg / L) were lower than those of the control group( 1. 05 ± 0. 24 vs 1. 98 ± 0. 15,10. 18 ± 4. 36 vs 24. 36 ± 7. 23),there had statistical difference( P < 0. 05). Conclusion Integrated traditional Chinese and western medicine in the treatment of postoperative intestinal paralysis of rectal carcinoma can relieve the patients’ symptoms,improve gastrointestinal function,and prevent gastrointestinal function failure.