食管癌术后发生呼吸系统并发症的影响因素研究

Influencing Factors of Respiratory Complications in Esophageal Cancer Patients after Surgery

目的探究影响食管癌患者术后呼吸系统并发症发生的危险因素。方法选取食管癌术后发生呼吸系统并发症(观察组)与未发生呼吸系统并发症(对照组)的食管癌患者各32例,术前均进行血常规、心电图以及各器官功能检查,并监测各项并发症情况。结果观察组患者平均年龄高于对照组[(66.64±12.66)岁VS(54.43±10.73)岁];手术时间也较对照组长;术前肺功能检查结果表明,发生呼吸系统并发症的患者MVV%、FEV1%得分[(49.64±5.43)、(38.42±4.97)分]明显低于未发生呼吸系统并发症患者的[(80.36±6.11)、(68.24±4.55)分],观察组和对照组术前并发症发生率分别为81.3%、46.9%,差异显著,具有统计学意义(P<0.05)。结论年龄、吸烟史、术前并发症、术后并发症个数、呼吸衰竭合并各类疾病、手术时间以及术后吻合口瘘等,均为影响患者术后呼吸系统并发症的独立危险因素。

Objective To explore the risk factors for postoperative respiratory complications in esophageal cancer patients. Methods Esophageal cancer patients with postoperative respiratory complications was the observation group,and without postoperative respiratory complications was the control group,each with 32 cases. All patients underwent preoperative blood,ECG and organ function checks,and various complications were monitored. Results The average age of the observation group were higher than that of the control group( 66. 64 ± 12. 66 years older than 54. 43 ± 10. 73 years); surgical time was longer compared to the control group; preoperative pulmonary function test results showed that MVV%,FEV1% scores in the patients with postoperative respiratory complications( 49. 64 ± 5. 43,38. 42 ± 4. 97) were significantly lower than those without postoperative respiratory complications( 80. 36 ± 6. 11,68. 24 ± 4. 55),the incidence of preoperative complications in the observation group and the control group were 81. 3% and 46. 9%,respectively,the difference was significant( P < 0. 05). Conclusion Age,smoking history,preoperative complications,the number of postoperative complications,respiratory failure with various diseases,operative time and postoperative anastomotic leakage are independent risk factors for postoperative respiratory complications in esophageal cancer patients.