显微手术对功能区矢状窦镰旁脑膜瘤患者的疗效

Efficacy of Microsurgery for Parasagittal and Parafalcine Meningioma in Functional Area

目的比较和分析常规手术与显微神经外科手术治疗功能区矢状窦大脑镰旁脑膜瘤的临床疗效。方法选取功能区矢状窦镰旁脑膜瘤患者作为研究对象,2003年6月前收治的44例作为对照组采用常规手术治疗;2003年6月后收治的40例作为研究组采用显微外科手术治疗,比较两组的临床疗效。结果研究组肿瘤全切除率为84.1%,高于对照组的57.5%(χ2=7.259);研究组术中平均输血量为(389.2±210.3)ml,低于对照组的(1 058.4+386.2)ml;研究组平均手术时间为(75.6+18.8)min,高于对照组的(50.4+12.2)min;研究组症状改善42例(95.5%),高于对照组的31例(77.5%),两组在肿瘤全切除率、术中输血量、手术时间和术后症状改善率等方面比较差异有统计学意义(P<0.05)。结论显微外科手术方法治疗功能区矢状窦镰旁脑膜瘤,可提高患者术后生存质量,临床疗效显著,值得在临床上进一步推广。

Objective To compare and analyze the clinical efficacy of conventional surgery and microsurgery in treatment of parasagittal and parafalcine meningioma(PPM) in functional area.Methods A series of patients with PPM in functional area were collected.44 cases underwent routine surgical treatment was the control group,40 cases received the microsurgery treatment was the experimental group.Clinical efficacy of the 2 groups was compared.Results In the experimental group,complete resection rate was 84.1%,mean blood loss was(389.2 ± 210.3) ml,symptom improvement rate was 95.5%,average operative duration was(75.6 + 18.8) min.In the control group,complete resection rate was 57.5%,mean blood loss was(1 058.4 ±386.2) ml,symptom improvement rate was 77.5%,average operative duration was(50.4 + 12.2) min.There were significant difference in complete resection rate,blood loss,operative duration,and symptom improvement rate(P < 0.05) between the 2groups.Conclusion Microsurgery for PPM in functional area can improve survival outcome and has a significant clinical effect.It is worthy of further clinical promotion.