神经内镜辅助经单鼻孔蝶窦入路垂体腺瘤切除术的临床效果分析

Clinical Analysis of Neuroendoscope-assisted Microsurgery Through Endonasal Transsphenoidal Approach for Pituitary Adenomas

目的探讨神经内镜辅助经单鼻孔-蝶窦入路切除垂体腺瘤的临床效果。方法将87例垂体腺瘤患者进行分组。神经内镜辅助经单鼻孔蝶窦入路切除垂体腺瘤49例(神经内镜组),显微镜下经单鼻孔蝶窦入路切除垂体腺瘤38例(显微镜组)。所有患者术后均随访6个月,比较两组垂体肿瘤切除术的疗效。结果神经内镜组患者肿瘤全切除率、术中出血量、手术持续时间、住院时间、并发症发生率及随访激素水平好转率均明显优于显微镜组。结论与传统显微镜手术比较,神经内镜辅助经单鼻孔蝶窦入路切除垂体腺瘤,临床效果肯定、预后较好,是垂体腺瘤理想手术方式,值得推广应用。

Objective To explore the clinical efficacy of neuroendoscope-assisted microsurgery through endonasal transsphenoidal approach for pituitary adenomas. Methods 87 patients with pituitary adenomas were divided into 2 groups. Neuroendoscope group( n = 49) received neuroendoscope-assisted microsurgery through endonasal transsphenoidal approach,microscope group( n = 38) received microsurgery through endonasal transsphenoidal approach. Then efficacy of the 2 groups were compared.The follow-up period was 6 months. Results The rate of complete tumor resection,intraoperative bleeding,duration of operation time,hospitalization time,incidence of complications and follow-up hormone level improvement in neuroendoscope group were all significantly superior to those of microscope group. Conclusion Compared with the conventional microscope group,the neuroendoscope-assisted microsurgery for pituitary adenoma has better clinical effects and prognosis,and it is an ideal treatment and is worthy of promotion.