不同靶浓度瑞芬太尼在老年患者胸科手术麻醉中的临床价值

The Clinical Value of Different Concentration of Remifentanil in Anesthesia of Elderly Patient Treated with Thoracic Surgery

目的探讨不同靶浓度瑞芬太尼在老年患者胸科手术麻醉中的效果与安全性。方法将进行手术的96例老年患者随机分为A、B、C 3组,每组32例。A组患者接受4μg/L瑞芬太尼麻醉,B组患者接受6μg/L瑞芬太尼麻醉,C组接受8μg/L瑞芬太尼麻醉。比较3组患者术中应激反应发生情况及综合指标。结果 3组患者术中情况(P>0.05);B组患者综合指标明显优于A、C组患者(P<0.05),A、C组患者综合指标比较,P>0.05;C组患者苏醒时间明显长于A、B组。结论 6μg/L瑞芬太尼应用于老年患者胸科手术中安全性高、能有效降低患者术中应激反应。

Objective To investigate the efficacy and the safety of different concentration of remifentanil in anesthesia of elderly patient treated with thoracic surgery. Methods 96 elderly patients treated with thoracic surgery were divided into A,B,C groups,each group with 32 cases. Group A were anaesthetized by 4 μg / L remifentanil,group B were anaesthetized by 6 μg / L remifentanil and group C were anaesthetized by 8 μg / L remifentanil. Emergency response and integrated indicators during the surgery of the 3 groups were compared. Results Intraoperative situation of the 3 groups had no significant difference( P > 0. 05),the integrated indicators of group B was significantly better than those of group A and B( P < 0. 05),and the integrated indicators of group A and group B had no significant difference( P > 0. 05). The awaking time of group C was obviously longer than those of group A and group B. Conclusion 6 μg / L remifentanil in anesthesia of elderly patient treated with thoracic surgery has high safety and can effectively reduce patient’s intraoperative emergency response.