晚期非小细胞肺癌化疗后中医药巩固治疗的疗效分析

Analysis of Therapeutic Effect of Traditional Chinese Medicine Consolidate Treatment for Advanced Non-small Cell Lung Cancer after Chemotherapy

目的探讨晚期非小细胞肺癌(NSCLC)化疗后中医巩固治疗的临床效果。方法选取120例晚期非小细胞肺癌患者作为研究对象,采取等距抽样法随机将其分为化疗组与中医组,各60例。化疗组实施持续化疗治疗,中医组则在化疗后实施中医巩固治疗。对比观察2组患者的治疗效果。结果中医组治疗总有效率为16.7%,化疗组治疗总有效率为10.0%,2组治疗效果对比,差异无统计学意义,P>0.05。中医组患者疾病无进展时间平均值(6.5±0.3)个月,中位值(5.1±0.6)个月,稍长于化疗组患者平均值(5.3±0.6)个月,中位值(4.1±0.6)个月,组间对比差异有统计学意义,P<0.05。结论对晚期NSCLC患者的治疗,可在参照其前期化疗效果与遵循患者主观意愿的前提下,后续选择中医药巩固治疗。

Objective To investigate the clinical efficacy of traditional chinese medicine( TCM) consolidate treatment for advanced non-small cell lung cancer( NSCLC) after chemotherapy. Methods 120 cases of advanced NSCLC,according to equidistant sampling method,were randomly divided into the chemotherapy group and the TCM group,each with 60 cases. The chemotherapy group received continuous chemotherapy,the TCM group received TCM consolidate treatment after chemotherapy,efficacy of the 2 groups were compared. Results Total effective rate in the TCM group was 16. 7%,and that of the treatment group was 10. 0%,there had no significant difference between the 2 groups,P > 0. 05. Average progression free time of the TCM group was( 6. 5 ± 0. 3) months,the median value was( 5. 1 ± 0. 6) months,which was slightly longer than that of the chemotherapy group( 5. 3 ± 0. 6) months,( 4. 1 ± 0. 6) months,there had significant differences between the 2 groups,P < 0. 05. Conclusion For advanced NSCLC patients,in reference to its previous effect of chemotherapy and subjective willingness of patients,TCM is selected as the subsequent consolidation therapy.