湖北省西北地区食管癌合并念珠菌感染的临床研究

Clinical Study of Esophageal Cancer with Candida Infection in Northwest Area of Hubei

目的探讨湖北省西北地区食管癌合并念珠菌感染的原因及治疗。方法抽取湖北省西北地区肿瘤科食管癌患者356例,回顾性分析356例食管癌患者的基本临床资料。结果食管癌合并感染发生率为19.94%。主要易感因素有:年龄>65岁,系统感染病史,免疫力低下、多个周期化疗、免疫抑制剂的应用及长期应用抗菌素。结论年龄因素、合并慢性病、感染因素、化疗方法、抗生素的使用等是导致食管癌发生念珠菌感染的重要原因,增强意识,早期诊断、早期规范治疗是及时控制感染的有效途经。

Objective To study esophageal cancer with candida infection in northwest area of Hubei and its treatment.Methods Clinical data of 356 cases of esophageal cancer from northwest area of Hubei received retrospective analysis. Results The infection rate of esophageal cancer was 19. 94%. The main risk factors were: age > 65,other system infection history,low immunity,multiple cycles of chemotherapy,the application of immunosuppressant and the long-term application of antibiotics. Conclusion Age,merging,chronic disease,infection factors,chemotherapy and use of antibiotics are important reasons for candida infection in esophageal cancer,strengthen awareness,early diagnosis,and early treatment are effective and timely method to control infection.