CT引导下穿刺活检表皮生长因子受体表达对于肺癌诊断的价值

The Diagnostic Value of CT-guided Needle Biopsy of the Epidermal Growth Factor Receptor Expression in Lung Cancer

目的探讨CT引导下穿刺活检表皮生长因子受体表达对于肺癌的诊断价值。方法选择行穿刺活检的肺癌患者72例,根据随机抽签原则分为2组,各36例。B超组采用B超引导下穿刺活检,CT组采用CT引导下穿刺活检。结果 CT组的一次性穿刺成功为100.0%,B超组为86.1%,差异有统计学意义(P<0.05)。CT组的肺癌检出率为91.7%,而B超组的肺癌检出率为86.1%,差异无统计学意义(P>0.05)。表皮生长因子受体在CT组中的阳性表达率为97.2%,在B超组中的阳性表达率为83.3%,组间对比差异有统计学意义(P<0.05)。穿刺过程中CT组的气胸、痰血等并发症发生率明显少于B超组,对比差异明显(P<0.05)。结论 CT引导下穿刺活检在肺癌中的诊断有很好的定位价值,可以提高穿刺活检的准确性,有利于表皮生长因子受体的表达检测,且能够减少并发症的发生。

Objective To investigate the diagnostic value of CT-guided needle biopsy of the epidermal growth factor receptor expression in lung cancer. Methods 72 lung cancer patients were equally divided into the CT group and the ultrasound group( group B). Group B received ultrasound-guided biopsy,and the CT group received CT-guided biopsy. Results The disposable puncture success rates in the CT group and the group B were 100. 0% and 86. 1%,there had statistically significant difference( P < 0. 05). The lung cancer detection rate in the CT group was 91. 7%,while that of the group B was 86. 1%,there had no significant difference( P > 0. 05). The positive expression of epidermal growth factor receptor in the CT group was 97. 2%,and that of the group B was 83. 3%,there had statistically significant difference( P < 0. 05). Incidence of pneumothorax puncture and blood sputum in the CT group were significantly less than the B group( P < 0. 05). Conclusion CT-guided biopsy in the diagnosis of lung cancer has better value,it can improve the accuracy of biopsy,reduce the incidence of complications,and it is beneficial for the detection of the expression of epidermal growth factor receptor.