恶性胸膜间皮瘤13例临床分析

Clinical Analysis of 13 Cases of Malignant Pleural Mesothelioma

目的分析恶性胸膜间皮瘤(MPM)的病因、临床表现、辅助检查、诊断及鉴别诊断。方法回顾性分析经临床病理确诊为恶性胸膜间皮瘤13例患者的临床资料。结果全组均行CT扫描检查,13例全为弥漫性胸膜增厚;8例经胸腔镜检查确诊,占61.5%,开胸活检确诊3例,占23.1%,CT引导下经皮肺穿刺确诊2例,占15.4%。结论恶性胸膜间皮瘤发病率低,诊断较困难,极易误诊,建议尽早行胸腔镜胸膜活检术,准确诊断本病有赖于组织病理学检查结合特异性免疫组织化学染色。

Objective To analyze the etiology,clinical manifestation,auxiliary examination,diagnosis and differential diagnosis of malignant pleural mesothelioma( MPM). Methods A retrospective study of the clinical data of 13 patients who were pathologically diagnosed with MPM were conducted. Results All cases were performed with CT scan,13 cases were all diffuse irregular pleural thickening,8 cases were diagnosed by thoracoscopy,accounting for 61. 5%,thoracic biopsy confirmed 3 cases,accounting for 23. 1%,percutaneous lung biopsy guided by CT confirmed 2 cases,accounting for 15. 4%. Conclusion MPM has low incidence and difficult diagnosis,It is recommended to conduct thoracoscopic pleural biopsy as early as possible. The accurate diagnosis of MPM depends on histopathological examination combined with specific immunohistochemical staining.