普罗帕酮治疗阵发性心房颤动20例临床观察

70 cases clinical observation of propafenone in treatments of paroxysmal atrial fibrillation.

目的通过静脉注射盐酸普罗帕酮注射液治疗阵发性心房颤动的疗效观察。方法对1997年11月至2002年7月广东省中山市博爱医院收治的20例阵发性心房颤动患者,用普罗帕酮注射液每次70～210 mg的总量,静脉注射后,观察并记录心率、血压情况,了解其对病人血压、心率等的影响。结果本组20例中阵发性心房颤动注射普罗帕酮注射液后有17例获转复,总有效率达85%。17例均在注射药物后8～51 min 内转复,平均转复时间(22.8±15)min;注射普罗帕酮注射液后血压均平稳。结论普罗帕酮注射液治疗阵发性心房颤动,起效较快,副反应少,安全,实用性好。

Objective Pass the intravenous the hydrochloride propafenone injection treatment the paroxysmal atrial fi- brillation curative effect the observation.Methods Choose into of 20 cases electrocardiograms diagnosis paroxysmal at- rial fibrillation use the propafenone injection 70～210 mgs/times total deal,after intravenous,Observe and record heart electricity,blood pressure circumstance,variety circumstance for record the electrocardiogram of not certain period, The understand effect blood pressure and heart rate patient of et al.Results This clinical 20 case paroxysmal atrial fi- brillation use the hydrochloride propafenone injection; Reach 17 cases get to curative eardioversion resume,the total va- lidity rate amount to 85%,17 clinical cases is all after intravenous propafenone injection the 8～52 minutes resume,It is average restore sinus rhythm of the heart time(22.8±15 minutes).After intravenous propafenone injection to the blood pressure is all steady:Conclusion The treatment cures the paroxysmal atrial fibrillation,Rise the effect more quickly,and the side effect is little,safety,the effect is fine.