巨幼红细胞性贫血的细胞形态学分析

The cell morphological analysis of megaloblastic anemia.

目的通过对巨幼细胞性贫血(MA)的细胞形态学分析总结,为准确诊断 MA 提供形态基础。方法于1999—2005年分析26例 MA 患者的外周血象变化及骨髓中病态红、粒细胞,病态巨核细胞和可染铁的变化。结果 26例患者中,外周血除贫血外,2系减少14例,3系减少8例,骨髓象26例都出现形态学病理改变。结论充分认识 MA 的细胞形态学特征,有助于准确诊断 MA,避免与其他血液病发生混淆。

Objective To diagnosis megaloblastic anemia (MA) rightly by analysing cell morphology.Methods To analyse the change of hemogram in peripheral blood and abnormal erythrocyte,granulocyte,macropolycyte and dyeabili- ty iron in bone marrow with 26 patients who suffered from MA.Results Besides anemia,there are 14 cases appearing two kinds of hematopoietic cell decrease and 8 cases appearing three kinds of them decrease.The bone marrow morpholo- gy is abnormal in all patients.Conclusion Identify adequately the morphological character of MA is benefit to diagnosis MA and differentiate medullar dysfunction syndrom (MDS),hemolytic anemia (HA) and aplastic anemia (AA)