醒脑静联合依达拉奉治疗急性脑梗死昏迷疗效观察

Observation of Xingnaojing injection combined with edaravone in treatment of acute cerebral infarction curative effect of coma

目的观察醒脑静注射液联合依达拉奉注射液治疗急性脑梗死昏迷患者的疗效。方法将黄石市中心医院2014年1—12月58例脑梗死昏迷患者随机分为治疗组和对照组。对照组采用脑梗死常规治疗(阿司匹林、奥扎格雷、低分子右旋糖苷、丹参注射液),治疗组在对照组的基础上加用醒脑静联合依达拉奉。临床治疗前后疗效以欧洲卒中评分(ESS)、格拉斯哥昏迷评分(GCS)作为评价标准。结果治疗14 d后治疗组的GCS及ESS评分与对照组比较均差异有统计学意义(P<0.05)。结论醒脑静注射液联合依达拉奉注射液对促进急性脑梗死昏迷患者神经功能缺损恢复及意识障碍改善是有效的。

Objective To observe the curative effect of Xingnaojing injection combined with edaravone injection therapy in patients with acute cerebral infarction coma. Methods From January 2014 to December 2014, 58 cases of cerebral infarction patients in coma were randomly divided into treatment group and control group of Huangshi central hospital. The control group conventional treatment for cerebral infarction(Ozagrel, aspirin, low molecular dextran, Salvia miltiorrhiza injection), the treatment group in the control group based on the use of edaravone combined with Xingnaojing injection. Clinical curative effect before and after treatment with the European Stroke Scale(ESs), Glasgow coma score(GCS) as the evaluation standard. Results After 14 days of therapy the treatment group of GCS and ESS score compared with the control group were obvious difference(P<0.05). Conclusion The improvement of Xingnaojing injection combined with Edaravone Injection on promoting nerve in patients with acute cerebral infarction coma recovery of functional defect and disturbance of consciousness is effective.