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多发性骨髓瘤治疗进展及其对预后的影响 被引量:1

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摘要 多发性骨髓瘤(MM)是浆细胞恶性肿瘤,好发于中老年人,其发病率居血液系统恶性肿瘤的第二位,约占血液系统恶性肿瘤的10%[1]。特征是骨髓中浆细胞克隆性增生积聚并分泌M蛋白,表现为溶骨性病变或骨质疏松及贫血、感染、肾功能损害等临床表现[2]。MM近年来发病率呈现逐步上升趋势,传统化疗的中位生存期不超过3年。约25%的患者能存活5年以上,存活10年的MM患者不到5%,
作者 沈君 王开泰
出处 《中国实用内科杂志》 CAS CSCD 北大核心 2015年第S1期166-169,共4页 Chinese Journal of Practical Internal Medicine
关键词 多发性骨髓瘤 治疗 预后 multiple myeloma treatment prognosis
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