幽门螺杆菌根除指征的演变

Evolution of Helicobacter pylori eradication indication

1994年,美国国立研究院提出根除幽门螺杆菌感染(Helicobacter pylori,Hp)的第一个适应证——消化道溃疡以来,关于Hp根除指征不断修改和扩大。2015年幽门螺杆菌胃炎京都全球共识提出:所有幽门螺杆菌感染者应予根除治疗,除非有抗衡方面考虑。即Hp根除不再需要指征。文章将结合中国五部幽门螺杆菌感染处理共识报告,对中国Hp根除指征的演变过程进行阐述,并展望中国未来Hp根除的适应证范围。

Since the National Institute of the United States proposed the first Helicobacter pylori(Hp)eradication indication,peptic ulcer,in 1994,the indications of Hp eradication has been modified and expanded continuously.In 2015,Kyoto global consensus report on Helicobacter pylori gastritis proposed that'H.pylori-infected individuals should be offered eradication therapy,unless there are competing considerations',which means that Hp eradication indications are no longer needed.This article aims to elaborate the evolution process of Hp eradication indications in China based on the five Chinese consensus reports of Hp infection treatment,and provide an outlook of the indications in the future.