心动过缓性心肌病

Bradycardia-induced cardiomyopathy

不仅持续性或反复性心动过速可引发心肌病,持久的缓慢性心律失常也可引起心肌病。心动过缓性心肌病的发病机制尚不明确,可能与心室舒张期显著延长、容量负荷过重、房室顺序收缩丧失、心室激动顺序改变、心室收缩不均一、心肌灌注不足等因素有关。诊断主要依据心动过缓病史、心脏扩大和心功能不全。主要治疗措施为心脏起搏器(特别是三腔起搏器)治疗,治疗后心功能可恢复正常。

Not only persistent or recurrent tachycardia,but also long-lasting bradyarrhythmia can induce cardiomyopathy. Its pathogenesis is not clear,which is possibly related to significantly prolonged ventricular diastole,overloaded volume,loss of atrioventricular sequential contraction,changes of ventricular activation sequence,heterogeneity of ventricular contraction,and myocardial hypoperfusion,etc. Diagnosis of the disease is mainly based on a medical history of bradycardia,cardiac dilatation,and cardiac functional insufficiency. By cardiac pacemaker( especially threechamber pacemaker) therapy,heart function can be back to normal.