心率减速力及QT离散度对慢性心力衰竭患者心源性猝死的预测价值

Clinical value of deceleration capacity and QT dispersion in predicting cardiac sudden death of patients with chronic heart failure

目的探讨心率减速力(deceleration capacity,DC)及QT离散度(QT dispersion,QTd)对慢性心力衰竭(chronic heart failure,CHF)患者心源性猝死的预测价值。方法随机选择慢性心力衰竭患者100例(心衰组),随访一年,根据有无室性心律失常分为室性心律失常组(43例)和非室性心律失常组(57例);根据有无心源性猝死分为猝死组(18例)和生存组(82例)。同期100例在本院体检健康者作为对照组。测定各组患者早期DC值和QTd值,进行统计分析。结果心衰组、室性心律失常组及猝死组患者的DC和QTd值分别和对照组、非室性心律失常组及生存组比较,差异均有统计学意义(P<0.05)。慢性心力衰竭患者的QTd与DC呈负性相关。结论慢性心力衰竭患者的DC和QTd值与病情严重程度有关,可作为预测慢性心力衰竭患者发生心源性猝死的敏感指标。

Objective To investigate the values of deceleration capacity( DC) and QT dispersion( QTd) in predicting cardiac sudden death( CSD) of patients with chronic heart failure( CHF).Methods One hundred CHF patients( CHF group) were randomly selected and followed up during one year.According to the existence of ventricular arrhythmia( VA),they were divided into VA group( 43 cases) and non-VA group( 57 cases).According to the existence of CSD,the enrolled cases were also divided into CSD group( 18 cases) and survival group( 82 cases).Meanwhile,another 100 healthy people examinated in our hospital were regarded as control group.In an early phase,the values of DC and QTd were measured in each group,and statistically analysed.Results Separately compared with control group,non-VA group,and survival group,differences of DC and QTd values were all statistically significant( P < 0.05) in CHF group,VA group,and CSD group,respectively.The value of QTd was negative to that of DC among CHF patients.Conclusion DC and QTd values of CHF patients were associated with the severity of attacks,which can be regarded as sensitive indices to predict CSD among CHF patients.