阿奇霉素序贯疗法治疗小儿支原体肺炎的临床疗效

Clinical Effects of Azithromycin Sequential Therapy in the Treatment of Mycoplasmal Pneumonia in Children

目的探讨阿奇霉素序贯疗法治疗小儿支原体肺炎的临床疗效。方法选取2014年5月—2016年4月中南大学湘雅医院收治的小儿支原体肺炎患儿102例,采用随机数字表法分为对照组50例与观察组52例。对照组患儿予以阿奇霉素治疗,观察组患儿予以阿奇霉素序贯疗法治疗。比较两组患儿临床疗效、不良反应发生率、体温恢复正常值时间、住院时间。结果观察组患儿总有效率高于对照组(P<0.05)。观察组患儿不良反应发生率低于对照组(P<0.05)。观察组患儿体温恢复正常值时间、住院时间短于对照组(P<0.05)。结论阿奇霉素序贯疗法治疗小儿支原体肺炎的临床疗效确切,可降低不良反应发生率,缩短体温恢复正常值时间和住院时间。

Objective To study the clinical effects of azithromycin sequential therapy in the treatment of mycoplasmal pneumonia in children. Methods A total of 102 children patients with mycoplasmal pneumonia in children in the Xiangya Hospital of Central South University from May 2014 to April 2016, they were dividren into control group( 50 cases) and observation group( 50 cases) according to random number table. Control group were given azithromycin treatment,observation group were given azithromycin sequential therapy treatment. Clinical effect, incidence of adverse reactions, the temperature returned to normal time and hospitalization time were comparde between the two groups. Results The total effective rate of the observation group was higher than the control group( P < 0. 05). Incidence of adverse reactions of the observation group was lower than that of the control group( P < 0. 05). The temperature returned to normal time and hospitalization time that of the observation group were shorter than those of the control group( P < 0. 05). Conclusion Azithromycin sequential therapy has certain clinical effect in traeting mycoplasmal pneumonia in children,can lower the incidence of adverse reactions,reduce the temperature returned to normal time and hospitalization time.