长春西汀注射液对于眩晕患者的日常生活自理能力和生活质量的影响观察与研究

Effect of Changchun Xiting Injection on the Self-care and Quality of Life of Dizziness Patients in Daily Life

目的本研究旨在评估长春西汀注射液对于眩晕患者的日常生活自理能力和生活质量的影响。方法 2014年1月—2017年6月在江苏省丹阳市人民医院神经内科接受治疗的眩晕患者40例,随机分为观察组和对照组,每组20例。观察组患者采用长春西汀注射液20mg+生理盐水250ml静脉滴注,加倍他司汀6mg,3次/d;对照组的患者采用倍他司汀6mg,3次/d。疗程均为2周。疗程结束后,定期随访3个月。对两组患者的日常生活自理能力和生活质量进行比较和分析。结果随访3个月时,观察组的Barthel评分明显,与治疗前和对照组比较,差异均有统计学意义(P<0.05)。另外,治疗组的SF-36得分明显增加,与治疗前和对照组比较,差异均有统计学意义(P<0.05)。结论长春西汀注射液可改善眩晕患者的日常生活自理能力和生活质量,值得在临床大力推广应用。

Objective This study was designed to evaluate the effect of Changchun Xiting injection on the daily life self-care ability and quality of life of patients with vertigo.Methods From January 2014 to June 2017,40 patients with vertigo treated by Department of Neurology were randomly divided into observation group and control group,20 cases in each group.The patients in the observation group were treated with vincristine injection 20 mg+saline 250 ml intravenously,plus oral betahistine 6 mg,tid;the control group of patients with oral betahistine 6 mg,tid.Treatment is 2 weeks.After the end of treatment,regular follow-up for 3 months.The self-care ability and quality of life of two groups were compared and analyzed.Results At 3 months follow-up,the Barthel score of the observation group was significantly different from before treatment and the control group(P<0.05).In addition,the SF-36 score of the treatment group was significantly increased,compared with before treatment and the control group,the difference was statistically significant(P<0.05).Conclusion Changchun Xiting injection can improve the self-care ability and quality of life of patients with vertigo.It is worthy to be popularized in clinical practice.