急诊脑外伤手术麻醉中应用舒芬太尼与瑞芬太尼的临床研究

Clinical Study of Sufentanil and Remifentanil in Emergency Anesthesia for Traumatic Brain Injury

目的分析舒芬太尼与瑞芬太尼应用于急诊脑外伤手术麻醉中的效果。方法 2015年2月—2018年2月,于北京市房山区第一医院收治的颅脑外伤急诊手术患者中选取88例,随机分为两组,各44例。麻醉过程中,对照组应用瑞芬太尼,观察组应用舒芬太尼,比较两组住院时间、气管拔管时间、苏醒时间、麻醉时间、不同时期心率、动脉压变化情况以及术后不良反应发生情况。结果观察组住院时间、气管拔管时间、苏醒时间明显短于对照组,差异有统计学意义(P<0.05);两组患者麻醉前以及术中MAP、心率比较,差异无统计学意义(P>0.05);观察组不良反应发生率为9.09%,对照组为13.64%,组间差异无统计学意义(χ~2=1.5287,P>0.05)。结论舒芬太尼与瑞芬太尼应用于急诊脑外伤手术麻醉中均能获得理想的麻醉效果,且舒芬太尼术后苏醒快、可控性好,能确保手术顺利进行。

Objective To analyze the effect of sufentanil and remifentanil in anesthesia for emergency traumatic brain injury.Methods From February 2015 to February 2018,88 patients who underwent emergency surgery for craniocerebral trauma admitted to Beijing Fangshan First Hospital were randomly divided into two groups,44 cases in each group.During the anesthesia,the control group was treated with remifentanil.Sufentanil was used in the observation group.Hospitalization time,tracheal extubation time,recovery time,anesthesia time,heart rate during different periods,arterial pressure changes and postoperative adverse reactions of two groups were compared.Results The length of hospital stay,tracheal extubation time,and recovery time in the observation group were significantly shorter than those in the control group,with significant differences(P<0.05).Before and during anesthesia,MAP and heart rate of two groups had no significant difference(P>0.05);The incidence of adverse reactions in the observation group was 9.09%,and that in the control group was 13.64%.There was no significant difference between the groups(χ~2=1.5287,P>0.05).Conclusion Sufentanil and remifentanil can achieve the ideal anesthetic effect in emergency anesthesia for emergency traumatic brain injury.Sufentanil has a quick recovery and good controllability,which can ensure the smooth operation.