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氯吡格雷联合芪参益气滴丸对冠心病心衰患者心功能的改善作用分析 被引量:4

Analysis of the Effect of Clopidogrel Combined with Qishen Yiqi Dropping Pill on Cardiac Function in Patients with Coronary Heart Disease and Heart Failure
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摘要 目的分析对冠心病心衰患者采取常规药物氯吡格雷与芪参益气滴丸共同治疗的临床效果,以及对患者心功能的改善作用。方法通过数字随机方法,将陕西省军区宝鸡第二干休所临床2017年8月—2018年8月接收并单纯服用氯吡格雷治疗的35例患者作为A组,另外选取同时间段接收并实施氯吡格雷与芪参益气滴丸共同治疗的35例同疾病患者作为B组,对两组的治疗效果、炎性因子水平变化情况和心功能的改善作用进行比较。结果 (1)B组LVEF水平高于A组,且LVESV、LVEDV水平低于A组(P<0.05);(2)B组CRP、TNF-α水平较A组低(P<0.05);(3)B组QOL评分较A组高(P<0.05);(4)B组治疗总有效率较A组高(P<0.05)。结论采取常规药物氯吡格雷与芪参益气滴丸共同治疗冠心病心衰的效果显著,价值颇高。 Objective To analyze the clinical effects of conventional drug clopidogrel and Qishen Yiqi Dropping Pill in patients with coronary heart disease and heart failure,and to improve the heart function of patients.Methods Thirty-five patients who received clopidogrel and received clopidogrel from August 2017 to August 18,2017 as a group A were randomly assigned to receive clopidogrel and sputum.35 patients with the same disease who were treated with Shenyi Pills were treated as group B,and the therapeutic effects,changes of inflammatory factor levels and improvement of cardiac function were compared between the two groups.Results(1)The level of LVEF in group B was higher than that in group A,and the levels of LVESV and LVEDV were lower than those in group A(P<0.05).(2)The levels of CRP and TNF-group B was highe lower than those in group A(P<0.05);(3)The QOL score of group B was higher than that of group A(P<0.05);(4)The total effective rate of group B was higher than that of group A(P<0.05).Conclusion The conventional drug clopidogrel combined with Qishen Yiqi Dropping Pill is effective in treating heart failure of coronary heart disease with high value.
作者 曾军 廖艳 常快乐 ZENG Jun;LIAO Yan;CHANG Kuai-le(Shanxi Military Region Baoji Second Cadre Rest,Baoji 721045,China;Department of Cardiology,The 987 Hospital of Chinese People's Liberation Army,Baoji 721004,China)
出处 《实用心脑肺血管病杂志》 2018年第A02期218-220,共3页 Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
关键词 冠心病心衰 氯吡格雷 芪参益气滴丸 治疗效果 Coronary heart disease heart failure Clopidogrel Qishen Yiqi dripping pills Therapeutic effect
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  • 1李军,李国,邵建华.无症状性心肌缺血[J].新医学,2005,36(12):734-735. 被引量:18
  • 2中华神经学会 中华神经外科学会.各类脑血管疾病诊断要点.中华神经科杂志,2006,:60-61.
  • 3中华医学会心血管病学分会.心血管疾病防治指南和共识2010[M].北京:人民卫生出版社,2010.1-15.
  • 4DIBRA A,MCHILLI J,BRAUN S,et al.Association between C-reactive protein levels and subsequent cardiac events among patients with stable angina treated with coronary artery stenting [J].Am J Med,2003,114(9):715-722.
  • 5YAN J C,ZHU J,GAO L,et al.The effect of elevated serum solu-ble CD40 ligand on the prognostie value in patients with acute coro-nary syndromes [ J ].Clin Chim Acta,2004,343(1/2):155-159.
  • 6GULDIKEN S,DEMIR M,ARIKAN E,et al.The levels of circu-lating markers of arteriosclerosis and inflammation in subjects with different degrees of body mass index:soluble CD40 ligand and high-sensitivity C-reactive protein[J].Thromb Res,2007,119(1):79-84.
  • 7MUHLESTEIN J B.Effect of anti-platelet therapy on innammalo-ry markers in athemthrombotie patients [ J ].Thromb Haemost,2010,103(1):71-82.
  • 8HEESCHEN C,DIMMELER S,HAMM C W,et al.Soluble CD40 ligand in acute coronary syndromes[J].N Engl J Med,2003,348(12):1104-1111.
  • 9PHIPPS R P.Atheroselerosis:the emerging role of the inflamma-tion and the CD40-CD40L ligand system[ J].Proc Natl Acad Sci U S A,2000,97(13):6930-6932.
  • 10QUINN M J,BHATT D L,ZIDAR F,et al.Effect of clopidogrel pretreatment on inflammatory maker expression in patients under-going percutaneous coronary intervention [ J ].Am J Cardiol,2004,93(6):679-684.

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