摘要
肺炎克雷伯菌(KP)是导致临床感染的常见病原菌之一,近年来随着碳青霉烯类抗菌药物广泛使用,耐碳青霉烯肺炎克雷伯菌(CRKP)检出率不断升高、耐药性不断增强。CRKP致死率较高,对患者生命安全构成巨大威胁。本文综述了CRKP的流行病学、耐药现状、检测方法及预防等,以期为临床有效防治CRKP提供参考。
Klebsiella pneumoniae(KP)is one of common pathogens that leading to clinical infection.In recent years,detection rate and drug resistance of carbapenem resistant Klebsiella pneumoniae(CRKP)continually increased due to extensively use of carbapenem antibiotics.Fatality rate of patients with CRKP is relatively high,which seriously threatening the life safety of patients.This paper mainly reviewed the epidemiology,drug resistance status,detection method and prevention of CRKP,to provide a reference for effective prevention and treatment of CRKP on clinic.
作者
刘妍
元小冬
乔思佳
张萍淑
李佳慧
郑慧
LIU Yan;YUAN Xiaodong;QIAO Sijia;ZHANG Pingshu;LI Jiahui;ZHENG Hui(Kailuan General Hospital Affiliated to North China University of Science and Technology,Tangshan 063000,China;Hebei Key Laboratory of Neurobiological Function,Tangshan 063000,China)
出处
《实用心脑肺血管病杂志》
2019年第2期15-19,共5页
Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
基金
河北省医学科学研究重点课题(20150039)
关键词
肺炎克雷伯菌
耐碳青霉素烯
流行病学
耐药性
预防
综述
Klebsiella pneumoniae
Carbapenem-resistant
Epidemiology
Drug resistance
Prevention
Review