替格瑞洛联合阿司匹林治疗急性冠状动脉综合征的临床疗效

Clinical Efficacy of Tigerrillo Combined with Aspirin in the Treatment of Acute Coronary Syndrome

目的研究替格瑞洛联合阿司匹林治疗急性冠状动脉综合征的临床效果。方法选择辽河油田总医院2017年1月—2017年12月中200例急性冠状动脉综合征患者进行研究,按照患者接受治疗的药物不同进行分组,观察组100例患者接受替格瑞洛联合阿司匹林治疗,对照组100例患者仅接受阿司匹林治疗,比较两组临床治疗效果。结果观察组患者治疗后cTnT、BNP、CRP水平均明显低于对照组(P<0.05);观察组治疗后心肌梗死每周发生次数及每次发作持续时间分别为(2.30±0.29)次/周、(1.67±0.22)min/次,均明显少于对照组(4.28±0.42)次/周、(4.19±0.37)min/次,P<0.05;观察组治疗后不良反应发生率为3%,与对照组不良反应发生率4%比较,差异无统计学意义(P>0.05)。结论替格瑞洛联合阿司匹林治疗急性冠状动脉综合征能够迅速改善患者临床症状,且不会影响治疗安全性,值得临床推广。

Objective To study the clinical effect of tigerrillo combined with aspirin in the treatment of acute coronary syndrome.Methods From January 2017 to December 2017,200 cases of patients with acute coronary syndromes are studied,according to different group,patients receiving treatment of drug group 100 patients accepted for Greg with aspirin therapy,the control group,100 cases of patients treated with aspirin alone,clinical therapeutic effect of two groups were compared.Results After treatment,cTnT,BNP and CRP levels in the observation group were significantly lower than those in the control group,P<0.05.After treatment,the weekly incidence of myocardial infarction and the duration of each attack were respectively(2.30±0.29)times/week,(1.67±0.22)minutes/time,significantly lower than that of the control group(4.28±0.42)times/week,and(4.19±0.37)minutes/time,P<0.05.The incidence of adverse reactions was 3%in the observation group after treatment,but there was no statistically significant difference from 4%in the control group,P>0.05.Conclusion The treatment of acute coronary syndrome by tigerrillo combined with aspirin can rapidly improve the clinical symptoms of patients without affecting the safety of treatment.