摘要
应用双波长薄层扫描法测定了鸦胆子果实中鸦胆苦醇的含量;为降低毒性,增强活性,试验合成了双鸦胆苦醇丙二酸酯。
Brusatol,which has proved to be a potential antitumor agent,was isolated from the traditional Chinese medicine "Yadanzi" (Brucea javanica(L.)Merr). The content (w/w) of brusatol in this plant was determined to be 2.7‰. The synthesis of 3,3-bisbrusatolyl malonate was carried out successfully.
出处
《沈阳药科大学学报》
CAS
1987年第4期262-264,239,共4页
Journal of Shenyang Pharmaceutical University
关键词
鸦胆苦醇
双波长扫描
双鸦胆苦醇丙二酸酯
苦木科
Brusatol
Dual wavelength TLC scanner
3
3-bisbrusatolyl malonate
Simaroubaceae
