原发性阴道恶性肿瘤19例临床诊治体会

Clinical Analysis of 19 Examples of Primarily Vaginal Mmalignant Tumor

目的:探讨原发性阴道恶性肿瘤的治疗方法及预后相关因素。方法:对19例原发性阴道恶性肿瘤进行回顾性分析,其中放疗17例(包括手术加放疗2例),手术4例,手术加化疗3例,放疗加化疗10例。结果:总5a生存率63.2%,临床分期为Ⅰ期、Ⅱ期、Ⅲ期、Ⅳ期5a生存率分别为83.3%、66.7%、33.3%、0%。结论:原发性阴道恶性肿瘤的治疗方法首选放疗,以放疗为主,早期病例可选择手术治疗,化疗为辅是目前比较合适的治疗方式。独立的预后因素为病理类型、阴道受侵长度、临床分期。早发现、早治疗、合理的放疗剂量分布及适合的剂量是提高生存率的关键。

Objective To study the therapies and prognosis factors of primarily vaginal maligmant tumor.Methods A retrospective analysis was estabilished in 19 examples of primarily vaginal malignant tumor,of which 17 received radiotherapy(including 2 received both operation andradiotherapy),4 received operation,3 received both operation and chemotherapy,10 received both radiotherapy and chemotherapy.Results The total five-year survival rate was 63.2%,the five-year survival rates were 83.3%、66.7%、33.3%、0% of clinical stageⅠ、 Ⅱ、 Ⅲ、 Ⅳ respectively.Conclusion The prefer method of primarily vaginal malignant tumor is radiotherapy.Nowadays,the rather effective therapeutics include using radiotherapy mainly,cases of early stage may using operation,and using chemotherapy assistantly.The independent factors of prognosis are pathological type、the length of vagina invaded and clinical stage.The early detection、early treatment and advisable radiological dose together with the distribution are key points of survival rates.