三种检查肺癌方法的结果分析

Analysis of the results of three methods for detecting lung cancer

目的探究癌胚抗原(CEA)血清学、细胞学、影像学检测以及三者联合检测对肺癌的诊断价值。方法对358例住院患者进行血清CEA和纤维支气管镜刷片细胞学检测,然后对血清CEA检测阳性的156例患者同时进行肺部CT检测,将3种检查结果进行比较分析。结果 358例进行血清CEA检测的患者中有156例阳性;358例进行纤维支气管镜刷片细胞学检测的患者中有97例阳性;156例CEA阳性病例进行肺部CT检查,其结果中有79例阳性;202例CEA阴性的病例进行肺部CT检查,结果均为阴性。临床最终诊断为肺癌的患者有83例。结论在肺癌的筛查方法中,血清学方法灵敏度高,但特异度较低;细胞学检测特异度高,是肺癌的确诊指标;CT检查特异度高并可以初步确定病变部位;3种方法联合检测更有利于肺癌的早期诊断。

Objective To investigate the diagnostic value of serum carcino-embryonic antigen(CEA),cytology,imaging and combined examination of the three detection methods in the diagnosis of lung cancer.Methods A total of 358 hospitalized patients were enrolled in this study.All 358 patients had a serum CEA test and a bronchofiberscope brush test,156 patients whose serum CEA test were positive had a CT test.We compared and analyzed the three kinds of detection results.Results In 358 cases of serum CEA test,the positive numbers were 156;In 358 cases of bronchofiberscope brush test,the positive numbers were 97;In 156 CEA-positive cases of CT test,the positive numbers were 79.In 202 CEA-negative cases of CT test,the results were all negative.Patients with clinical diagnosis of lung cancer were83.Conclusions In the screening methods of lung cancer,serum CEA test had high sensitivity and low specificity;Cytology test had a high specificity.It could be used as a definite diagnosis index.CT test had a high specificity.It could determine the location of the lesion.The combined detection of three methods was more conductive to the early diagnosis of lung cancer.