五丹散凝胶治疗糖尿病并牙周炎的临床疗效观察

The Clinical Efficacy of the Wudan San in the Treatment of Diabetes with Periodontitis

[目的]观察五丹散凝胶治疗糖尿病并牙周炎的临床疗效。[方法]2010年1月至2012年3月我院门诊就诊的糖尿病合并牙周炎100例患者,随机分为治疗组和对照组,其中治疗组在牙周基础治疗基础上使用五丹散凝胶,对照组在牙周基础治疗基础上使用四环素凝胶剂,记录牙周同一点治疗前和治疗后4周的牙周探诊深度(PD),牙龈指数(GI),探诊出血(BOP),菌斑指数(PLI)及附着丧失(AL)等指标。[结果]两组患者治疗前牙周指标差异均无明显的统计学意义(P】0.05),治疗后4周治疗组在PD,BOP,PLI和AL均较治疗前下降,其中PD,BOP和PLI治疗后水平低于对照组治疗后水平,差异有统计学意义(P【0.05)。[结论]五丹散凝胶治疗糖尿病并牙周炎有效,值得临床推广应用。

[Objective]To observe the clinical efficacy of Wudan San in the treatment of diabetes with periodontitis.[Methods]100 diabetes outpatients with periodontitis in our hospital from January 2010 to March 2012 were randomly divided into treatment and control groups.The treatment group’s patients were given Wudan San on the basis of initial periodontal therapy,On the other hand,the control group were given tetracycline gel.The periodontal probing depth(PD),gingival index(GI),bleeding on probing(BOP),bacteria plaque index(PLI) and attachment loss(AL) and other indicators were recorded in the same point before and 4 weeks after treatment.[Results]The differences of periodontal index in the two groups before treatment were not statistically significant(P> 0.05).The PD,BOP,PLI and Al of treatment group after 4 weeks were decreased than before treatment,which were significantly lower than the level in the control group,the difference was statistically significant(P<0.05).[Conclusion]Wudan San is effective in the treatment of diabetes with periodontitis and worthy of clinical application.