自拟调脂通脉汤联合洛伐他汀胶囊治疗高脂血症随机对照临床研究

Self-made Tiaozhi Tongmai Decoction Combined with Lovastatin Capsule in the Treatment of Hyperlipidemia,Randomized Controlled Clinical Study

[目的]观察自拟调脂通脉汤联合洛伐他汀胶囊治疗高脂血症临床疗效。[方法]将120例高脂血症患者随机分为两组。对照组50例常规应用西药洛伐他汀胶囊治疗,治疗组70例在应用洛伐他汀胶囊基础上加用中药调脂通脉汤(药用当归、桃仁、红花、柴胡、半夏等)。观测血液流变学变化,血脂变化。均以30d为1个疗程,连服2个疗程后判定疗效。[结果]治疗组临床症状、心电图疗效均优于对照组(P<0.05)。治疗前后血脂、血流变治疗组明显优于对照组(P<0.05)。[结论]中西医结合治疗高脂血症近远期疗效均显著。

[Objective]To observe the self-made Tiaozhi Tongmai Decoction Combined with lovastatin capsule in the treatment of hyperlipidemia,clinical efficacy.[Methods]120 patients with hyperlipidemia were randomly divided into two groups.50 cases of the control group routine application of lovastatin capsule in the treatment of Western medicine,treatment group and 70 cases in the application of lovastatin capsule combined with traditional Chinese medicine Tiaozhi Tongmai Decoction(medicinal angelica,peach kernel,safflower,bupleurum,Pinellia ternata,etc.).Observation of changes of blood rheology,the changes of blood lipids.By 30d for 1 courses,and even served 2 after treatment to determine efficacy of treatment.[Results]the treatment group of clinical symptoms,electrocardiogram curative effect was better than that of control group(P < 0.05).Blood lipid,blood rheology before and after treatment in treatment group than in control group(P < 0.05).[Conclusion]combination of traditional Chinese and Western medicine in treating hyperlipidemia in long term effects were significant.