参松养心胶囊治疗冠心病室性早搏随机平行对照研究

The Random Parallel Control Study of Shensong Yangxin Capsule In Treatment Of Coronary Heart Disease (Chd) of Ventricular Premature Beat

[目的]观察参松养心胶囊治疗冠心病室性早搏疗效。[方法]使用随机平行对照方法,将116例住院患者按就诊顺序编号随机分为两组。对照组60例比索洛尔5mg,1次/d,口服,1周后改为2.5mg,1次/d,2周后调整为1.25mg,1次/d。治疗组56例参松养心胶囊,4粒/次,3次/d,口服。连续治疗4周为1疗程。观测临床症状、24h动态心电图、肝肾功能、电解质、不良反应。连续治疗2疗程,判定疗效。[结果]治疗组显效38例,有效16例,无效2例,总有效率96.43%。对照组显效26例,有效19例,无效15例,总有效率75.00%。治疗组疗效优于对照组(P<0.05)。[结论]参松养心胶囊治疗冠心病室性早搏疗效满意。

[Objective]To observe the therapeutic effect of Shensongyangxin capsule in treatment of coronary heart disease with ventricular premature beats in patients with clinical efficacy.[Methods] Used random parallel control method,116 cases of hospitalized patients were divided into two groups according to clinic order numbering method。The control group was given 5mg Shensongyangxin capsule,1time / d,took orally,and insteaded by 2.5 mg after 1 week,1 time / d,then adjusted 1.25 mg,1time / d after 2 weeks.56 cases of the treatment group cured by shensong yangxin capsule,4 pellet / time,3 times / d,oral.4 weeks was 1 course of treatment;and then observated clinical symptoms,24 h dynamic electrocardiogram,liver and kidney function,electrolyte,and adverse reactions.After 2 courses of treatment continuously,judged curative effect.[Results]The treatment group 38 cases were markedly effective,effective in 16 cases,ineffective in 2 cases,the total effective rate was 96.43%;the control group 26 cases were markedly effective,effective in 19 cases,ineffective in 15 cases,the total efficiency of 75%.The curative effect of the treatment group was better than the control group(P < 0.05).[Conclusion] The curative effect is satisfied of shensong yangxin capsule in treatment of premature coronary artery disease.