川芎嗪联合西药治疗急性期尿石症随机平行对照研究

Chuanxiongqin Combined with Western Medicine in Treatment of Acute Urolithiasis Randomized Parallel Controlled Study

[目的]观察川芎嗪联合西药治疗急性期尿石症疗效。[方法]使用随机平行对照方法,将100例住院患者按就诊顺序编号法随机分为两组。对照组50例抗生素、西米替丁、维生素B6、654-2、黄体酮注射液、度冷丁等,并体外震波碎石。治疗组50例注射盐酸川芎嗪160mg+生理盐水250mL静滴,1次/d。西药治疗同对照组。连续治疗7 d为1疗程。观测临床症状、不良反应。连续治疗2疗程,判定疗效。[结果]治疗组治愈32例,好转16例,无效2例,总有效率96.00%。对照组治愈25例,好转19例,无效6例,总有效率88.00%。治疗组疗效优于对照组(P<0.05)。[结论]川芎嗪联合西药治疗急性期尿石症疗效显著,值得推广。

[Objective] observed tetromethylpyrazine efficacy of Western medicine treatment of acute urolithiasis.[ Methods] Using randomized controlled method,100 cases of hospitalized patients according to treatment were randomly divided into two groups sequentially numbered.Control group,50 cases of antibiotics,cimetidine,vitamin B6,654-2,progesterone injection,meperidine,etc.,and extracorporeal shock wave lithotripsy.Treatment group 50 cases ligustrazine hydrochloride 160mg + saline injection 250mL infusion,1 times / d.Western medicine with the control group.Continuous treatment 7 d as a course of treatment.Observation of clinical symptoms and adverse reactions.2 courses of continuous treatment,to determine efficacy.[Results] treatment group were cured 32 cases,improved in 16 cases,2 cases,the total efficiency of 96.00%.Control group,25 cases were cured,improved in 19 cases,6 cases,the total efficiency of 88.00%.Treatment group than the control group(P <0.05).[ Conclusion] tetromethylpyrazine western medicine treatment of acute urolithiasis effect is significant,worthy of promotion.