丹红注射液联合纳洛酮治疗急性酒精中毒随机平行对照研究

Then the Parallel Control Study of Danhong Injection Combined with Naloxone in Treatment of Acute Alcoholism

[目的]观察丹红注射液联合纳洛酮治疗急性酒精中毒疗效。[方法]使用随机平行对照方法,将100例住院患者按随机数字表法分为两组。对照组纳洛酮,0.8mg/次,1次/d,静滴。治疗组丹红注射液30mL+5%葡萄糖250mL,1次/d,静滴,西药治疗同对照组。观测临床症状、清醒时间、不良反应。连续治疗3个疗程,判定疗效。[结果]治疗组痊愈39例,显效8例,有效2例,无效1例,总有效率98.00%。对照组痊愈26例,显效10例,有效6例,无效8例,总有效率84.00%。治疗组疗效优于对照组(P<0.01)。清醒时间治疗组优于对照组(P<0.01)。[结论]丹红注射液联合纳洛酮治疗急性酒精中毒效果显著,值得推广。

[Objective]Observation of Danhong injection combined with naloxone in treatment of acute alcohol poisoning effect.[Methods]using randomized controlled methods,100 cases(hospital)were randomly divided into two groups).Control group,naloxone,0.8mg/time,1/d,intravenous drip.The treatment group Danhong injection,30mL/time,1/d,adding 5% glucose as auxiliary,intravenous drip,western medicine treatment with the control group.Observation of clinical symptoms,awake time,adverse reaction.Continuous treatment of 3 courses,the curative effect.[Results]the treatment group 39 cases were cured,8 cases markedly effective,effective 2 cases,invalid 1 cases,the total efficiency of 98%.The control group cured 26 cases,effective in 10 cases,effective 6 cases,invalid 8 cases,and the total efficiency of 84%.The efficacy of the treatment group than in control group(P<0.01).The treatment group was better than control group awake time(P<0.01).[Conclusion]The poisoning effect of Danhong injection combined with naloxone in treatment of acute alcohol is worth popularizing widely.