清肺平喘汤治疗小儿哮喘随机平行对照研究

Qingfei Pingchuan Soup Treatment of Infantile Asthma Random Parallel Control Study

[目的]观察清肺平喘汤治疗小儿哮喘疗效。[方法]使用随机平行对照方法,将80例门诊患者按随机数字表法随机分为两组。对照组40例吸氧、平喘、祛痰、抗感染等对症治疗。治疗组40例清肺平喘汤(生石膏15g,炙麻黄、白果、紫苏子各3g,杏仁、地骨皮各6g,地龙4g,黄芩3g,生甘草2g)1剂/d,水煎100mL,早晚口服。连续治疗7d为1疗程。观测临床症状、肺功能(FVC、FEV1、PEF)、不良反应。连续治疗1疗程,判定疗效。[结果]治疗组临床控制21例,显效14例,有效2例,无效3例,总有效率92.50%。对照组临床控制14例,显效10例,有效7例,无效9例,总有效率77.50%。治疗组疗效优于对照组(P<0.05)。肺功能指标(FVC、FEV1、PEF50及FEV1/FVC)两组均显著升高(P<0.05),组间无明显差异(P>0.05)[结论]清肺平喘汤治疗小儿哮喘效果显著,值得推广。

[Objective]To observe the Qingfei Pingchuan soup curative effect on children with moderate asthma attacks.[Methods]Using random parallel control method,80 cases of clinic patients were randomly divided into two groups according to random number table method.The control group,40 cases of oxygen,smooth wheezing,expectorant,anti-infection and relevant conventional symptomatic treatment.Treatment group 40 cases Qingfei Pingchuan soup,(Shengshigao15g,Zhimahuang、Baiguo、Zisuzi each 3g,Xingren、 Digupi 6g,4g Dilong,Huangchen 3g,Shenggancao 2g)1 agent/d,and 100 ml water,oral sooner or later.Contact treatment 7 d for 1 course of treatment.Observed the clinical effect and pulmonary function(FVC,FEV1 and PEF),adverse reactions.Continuous treatment 1 treatment course,judge curative effect.Clinical control.[Results]the treatment group 21 cases,14 cases were markedly effective,effective in 2 cases,3 had no effect,the total effective rate was 92.50%.Clinical control of 14 cases of control group,10 cases were markedly effective,effective 7 cases,9 no effect,the total effective rate was 77.50%.The treatment group curative effect is better than that of control group(P<0.05).Index of pulmonary function(FVC,FEV 1,PEF50 and FEV1 / FVC)in the two groups were significantly higher(P<0.05),no significant differences between groups(P>0.05).[Conclusion]soup treatment of infantile asthma clear lung effect is remarkable,is worth promoting.