强心补气方联合西药治疗肺心病急性加重期随机平行对照研究

Traditional Chinese Medicine Decoction Combined Western Medicine Treatment of Cor Pulmonale with Acute Aggravating Period of Random Parallel Control Study

[目的]观察强心补气方联合西药治疗肺心病急性加重期疗效。[方法]使用随机平行对照方法,将80例住院患者按随机数字表法分为两组。对照组40例控制感染、平喘、吸氧、利尿、抗心衰、平衡酸碱电解质。治疗组40例强心补气方(葶苈子、车前子各15g,丹参30g、桑白皮、赤芍各20g,当归、黄芪各12g,地龙、炒苏子、姜半夏、红花、茯苓、瓜蒌皮各10g),1剂/d,水煎400mL,早晚温服。西药治疗同对照组。连续治疗14d为1疗程。观测临床症状、血气分析、不良反应。连续治疗2疗程,判定疗效。[结果]治疗组显效38例,有效1例,无效1例,总有效率97.50%。对照组显效20例,有效8例,无效12例,总有效率70.00%。治疗组疗效优于对照组(P<0.01)。血气分析两组均有改善(P<0.01),治疗组改善优于对照组(P<0.01)。[结论]强心补气方联合西药治疗肺心病急性加重期具有见效快、疗效高的特点,值得推广。

[Objective]To observe the strong heart fill gas combined western medicine treatment of cor pulmonale with acute aggravating period of efficacy.[Methods]Using random parallel control method,80 cases of hospitalized patients into two groups according to random number table method.The control group,40 cases of western medicine therapy,infection control,and asthma,oxygen,diuresis,heart failure and other conventional treatment,acid-base balance,electrolytes.Treatment group(40 cases of application of strong heart fill gas side(Tinglizi,Chenqianzi each 15g,30gDanshen,Sangbaipi,Chishao each 20g,Danggui,Huangshi,12g,Dilong,Chaosuzi,Jiangbanxia,Honghua,Fuling,Gualoupi every 10g)1/d,and 400 mLwater,morning and evening temperature.Western medicine treatment with the control group.14 d continuous treatment for 1 course of treatment.Clinical curative effect observation,blood gas,adverse reactions.For 2 course of treatment(28d),to judge the curative effect.[Results]Team of 38 cases were markedly improved,effective in 1 case,1 had no effect,total effective rate was 97.50%.Control group 20 cases had marked effect,8 cases,12 cases ineffective,the total effective rate was 70.00%.The treatment group curative effect is better than that of control group(P<0.01).Strong heart fill gas side joint.[Conclusion]Western medicine treatment of cor pulmonale with acute aggravating period has the characteristics of quick effect,high curative effect,is worth promoting.