麻疹灌肠液联合西药治疗小儿麻疹随机平行对照研究

Measles Enema Combined with Western Medicine Treatment of Children with Measles Randomized Controlled Study

[目的]观察麻疹灌肠液联合西药治疗小儿麻疹疗效。[方法]使用随机平行对照方法,将108例门诊及住院患者按随机数字表法分为两组。对照组54例抗炎、对症治疗、支持治疗。治疗组54例前驱期,Ⅰ号麻疹灌肠液;出疹期,Ⅱ号麻疹灌肠液;恢复期,Ⅲ号麻疹灌肠液。水煎30～50mL,过滤分装。将分装好的药液加温至38℃左右,用50mL注射器抽吸适量2%奴夫卡因,再抽吸灌肠液保留灌肠,2次/d;将导管插入肛门内5～7cm,取灌肠液灌肠,灌肠后应将臀部抬高,仰卧30～40min,然后再右侧卧相同时间,2次/d。不同年龄段患儿所需灌肠液用量不同,5个月～1岁,10～20mL;1～3岁,20～30mL;3～6岁,30～50mL。西药治疗同对照组。连续治疗4～6d为1疗程。观测临床症状、症状体征变化时间、不良反应。连续治疗1疗程,判定疗效。[结果]治疗组治愈32例,好转20例,无效2例,总有效率96.30%。对照组治愈21例,好转24例,无效9例,总有效率83.33%。治疗组疗效优于对照组(P<0.05)。症状体征变化时间治疗组低于对照组(P<0.01)。[结论]麻疹灌肠液联合西药治疗小儿麻疹效果显著,值得推广。

[Objective]Observed measles enema combined with western medicine treatment of children with measles effect.[Methods]Using randomized controlled method,108 cases of outpatient and inpatient were randomly divided into two groups.Control group,54 cases of anti-inflammatory,symptomatic treatment and supportive treatment.Treatment group 54 cases prodromal period,Ⅰ number of measles enema;eruptive stage,Ⅱ number of measles enema;recovery,Ⅲ number of measles enema.Cook 30 ～ 50mL,filtered aliquots.The dispensing good liquid heated to about 38 ℃,50mL syringe pump with a moderate 2% novocaine,then pumped enema retention enema,2 times / d;catheter is inserted into the anus 5 ～ 7cm,take enema enema,enema should raise the hips,sit 30 ～ 40min,and then lying on the right side of the same time,2 times / d.Children of different ages need different amounts of enema,5 months to 1 year old,10 ～ 20mL;1 ～ 3 years old,20 ～ 30mL;3 ～ 6 years old,30 ～ 50mL.Western medicine with the control group.4 ～ 6d continuous treatment is a course of treatment.Observation of clinical symptoms,signs and symptoms change time,adverse reactions.Continuous treatment of a course of treatment,to determine efficacy.[Results]treatment group were cured 32 cases,improved in 20 cases,2 cases,the total efficiency of 96.30%.Control group,21 cases were cured,improved in 24 cases,9 cases,the total effective rate was 83.33%.Treatment group than the control group(P <0.05).Symptoms and signs change time treatment group than the control group(P <0.01).[Conclusion] Measles enema combined with western medicine treatment of children with measles effect is remarkable,worthy of promotion.