茵栀黄口服液联合蓝光照射治疗新生儿黄疸随机平行对照研究

Yinzhihuang Oral Liquid Combined with BluRay Irradiation Treatment of Neonatal Jaundice Of Random Parallel Control

[目的]观察茵栀黄口服液联合蓝光照射治疗新生儿黄疸疗效。[方法]使用随机平行对照方法,将60例住院患者按抽签方法随机分为两组。对照组30例蓝光照射治疗,1次/d。治疗组30例茵栀黄口服液5mL/次,2次/d。蓝光照射治疗同对照组。连续治疗7d为1疗程。观测临床症状、血清总胆红素(TBiL)、胆红素恢复时间、不良反应。连续治疗1疗程,判定疗效。[结果]治疗组显效15例,有效13例,无效2例,总有效率93.33%。对照组显效10例,有效11例,无效9例,总有效率70.00%。治疗组疗效优于对照组(P<0.05)。每日胆红素降低值治疗组优于对照组(P<0.01),胆红素恢复时间治疗组低于对照组(P<0.01)。[结论]茵栀黄口服液联合蓝光照射治疗新生儿黄疸效果显著,值得推广使用。

[Objective]To observe the therapeutic effect of Yinzhihuang oral liquid combined with blue light irradiation in the treatment of neonatal jaundice.[Method]Using randomized controlled Methods,60 patients were in the draw method were randomly divided into two groups.Blue light irradiation for treatment of 30 cases of control group,1 /d,30 cases in the treatment group of Yinzhihuang oral liquid 5mL/ times,2 times /d.The blue light treatment with the control group.Continuous treatment with 7d for 1 courses.Observation of clinical symptoms,serum total bilirubin(TBiL),bilirubin recovery time,adverse reaction.Continuous 1 courses of treatment,the curative effect.[Results]The treatment group was 15 cases,effective 13 cases,invalid 2 cases,the total efficiency of 93.33%.10 cases of control group,11 cases effective,9 cases ineffective,the total efficiency of 70.00%.The treatment group was better than control group(P<0.05).Daily bilirubin values in treatment group than in control group(P<0.01),bilirubin recovery time of treatment group was lower than control group(P<0.01).[Conclusion]The effect of Yinzhihuang oral liquid combined with Blu ray irradiation treatment of neonatal jaundice,obviously,is worth popularizing.