麻杏甘石汤联合西药治疗支气管哮喘随机平行对照研究

Maxing Ganshi Soup Combined with Western Medicine Treatment of Bronchial Asthma,Randomized Parallel Group Study

[目的]观察麻杏甘石汤联合西药治疗支气管哮喘疗效。[方法]使用随机平行对照方法,将56例住院/门诊患者按随机数字表法分为两组。对照组28例β2受体兴奋剂茶碱缓释片0.2g/次,2次/d;根据患者病情轻重分期吸入普米克气雾剂,200～1000μg/d。治疗组28例麻杏甘石汤(麻黄15g,石膏30g,杏仁20g,甘草10g);1剂/d,水煎250～300mL,分三次服用。风寒在表去石膏加荆芥、紫苏;风温而挟风寒加牛旁子、淡豆豉;发热甚加银花、鱼腥草、连翘;大便秘结加大黄;咳喘痰中带血加血余炭、白茅根;食欲纳差加山楂、建曲;肾不纳气加桂元肉、胡桃肉;舌质紫暗加红花、丹参。西药治疗同对照组。连续治疗7d为1疗程。观测临床症状、不良反应。连续治疗3疗程,判定疗效。[结果]治疗组显效20例,有效7例,无效1例,总有效率96.43%。对照组显效10例,有效15例,无效3例,总有效率89.29%。治疗组疗效优于对照组(P<0.05)。[结论]麻杏甘石汤联合西药治疗支气管哮喘效果显著,值得推广使用。

[Objective]Observe Ma Xing GanShi Tang combined with western medicine treatment of bronchial asthma treatment.[Methods]Using randomized controlled method,56 cases of inpatient / outpatient patients were randomly divided into two groups.Control group,28 cases of β2 agonist theophylline 0.2g / time,2 times / d;according to patient severity staging suck Rupumike aerosol,200 ～ 1000μg / d.Treatment group 28 cases Ma XingGan Shi Tang(Mahuang 15g,Shigao 30g,Xingren 20g,Gancao 10g);1 does / d,decoction 250 ～ 300mL,taking three times.Cold in the table to gypsum Nepeta,basil;wind chill temperature while relying on Canadian cattle next to the child,SSP;fever even add honeysuckle,Houttuynia,forsythia;constipation increased yellow;cough and bloody sputum plus blood over charcoal,cogongrass rhizome;appetite anorexia plus hawthorn,built song;kidney qi plus Guiyuan meat,walnut meat;dark purple tongue plus safflower,salvia.Western medicine with the control group.7d is a continuous course of treatment.Observation of clinical symptoms and adverse reactions.Continuous treatment of 3 courses,to determine efficacy.[Results]treatment group,20 cases markedly effective in 7 cases,1 case,the total effective rate 96.43%.Control group,10 cases markedly effective in 15 cases,3 cases,the total efficiency of 89.29%.Treatment group than the control group(P <0.05).[Conclusion]Ma XingGan Shi Tang combined with western medicine treatment of bronchial asthma,the effect is significant and should be introduced.