中药汤剂联合西药治疗支气管扩张症随机平行对照研究

Randomized Controlled Trial of Traditional Chinese Medicine Decoction Combined with Western Medicine in the Treatment of Bronchiectasis

[目的]观察中药汤剂联合西药治疗支气管扩张症疗效。[方法]使用随机平行对照方法,将52例门诊患者按随机数字表法分为两组。对照组25例①加强体位引流;②抗生素治疗;③止咳化痰;④咯血。治疗组27例风热犯肺型(败酱草、鲜芦根各30g,金银花20g,黄芩、前胡各12g,连翘、枇杷叶、陈皮、茯苓、制半夏、天竺黄、苏叶、白芷、荆芥、防风各10g,薄荷6g,甘草3g)。痰热壅肺型(鲜芦根、生米仁各60g,鱼腥草、败酱草各30g,火麻仁、郁李仁各15g,冬瓜仁、黄芩、天竺黄、陈皮、茯苓、半夏、扁豆炒、白术炒、枳壳各10g,甘草5g)。气阴两虚型(鱼腥草30g,北沙参、蛤壳各15g,麦冬、制黄精、陈皮、茯苓、乌元参、黄芪各10g,桔梗、木蝴蝶各6g,甘草5g)。1剂/d,水煎1000mL,早晚分服。西药治疗同对照组。连续治疗1周为1疗程。观测临床症状、血液生化指标、不良反应。连续治疗3疗程,判定疗效。[结果]治疗组显效18例,有效8例,无效1例,总有效率96.30%。对照组显效11例,有效9例,无效5例,总有效率80.00%。治疗组疗效优于对照组(P<0.05)。[结论]中药汤剂联合西药治疗支气管扩张症疗效显著,且未见明显不良反应,值得推广使用。

[Objective]To observe the effect decoction combined with western medicine treatment of bronchiectasis effect.[Methods]Using randomized controlled method,52 cases of outpatients were randomly divided into two groups.① control group,25 cases strengthen postural drainage;② antibiotics;③ cough and phlegm;④ hemoptysis.Treatment group 27 cases wind heat invading type(Baijiangcao,Xianlugen each 30g,Jinyinhua 20g,Huangqin,Qianhu each 12g,Lianqiao,Pipaye,Chenpi,Fuling,Zhibanxia,Tianzhu huang,Shuye,Baizhi,Jingjie,Fangfeng each 10g,Bohe 6g,Gancao 3g).Phlegm obstruct the lung type(Xianlugen,Shengmiren each 60g,Yuxingcao,Baijiangcao each 30g,Huomaren,Yuli ren each 15g,Dongguaren,Huangqin,Tianzhuhuang,Chenpi,Fuling,Banxia,biandou fried,Baishu fried,Zhike each 10g,Gancao 5g).Yin Deficiency type(Yuxingcao 30g,Beishashen,Hake each 15g,Maidong,Zhihuangjing,Chenpi,Fuling,Wuyuanshen,Huangqi each 10g,Jugeng,Muhudie each 6g,Gancao 5g).1 does/ d,decoction 1000mL,morning and evening service.Western medicine with the control group.Continuous treatment one week course of treatment.Observation of clinical symptoms,blood biochemical parameters,adverse reactions.Continuous treatment of 3 courses,to determine efficacy.[Results]treatment group,18 cases markedly effective in 8 cases,1 case,the total effective rate 96.30%.Control group,11 cases markedly effective in 9 cases,5 cases,the total efficiency of 80.00%.Treatment group than the control group(P<0.05)[.Conclusion] decoction combined with western medicine treatment of bronchiectasis effect is significant,and no significant adverse reactions,should be introduced.