扶正解毒汤联合CAG方案治疗急性髓系白血病19例临床观察

The Centralizer Jiedu Decoction Combined the CAG Patients with Acute Myeloid Leukemia 19 Cases of Clinical Observation

[目的]观察扶正解毒汤联合CAG方案治疗急性髓系白血病的疗效。[方法]对19例住院急性髓系白血病患者进行中西医结合治疗,CAG方案,阿糖胞苷,10mg/m2,1次/12h,皮下注射。第1~14d,阿柔比星,20mg/次,第1、3、5、7d,粒细胞集落刺激因子(G-CSF),200μg/m2,1次/d,皮下注射,第0~13d,白细胞数大于20×109/L时停用。中药治疗,扶正解毒汤,以扶助正气、驱邪解毒(,白花蛇舌草、黄芪、生地黄、景天三七各20g,太子参、天冬、麦冬、南沙参、北沙参、当归、白术、藤梨根、半枝莲、青黛、龙葵各10g,党参15g)。1剂/d,水煎100mL,早晚口服。连续治疗14d为1疗程。观测临床症状、不良反应。治疗1疗程,判定疗效。[结果]CR11例,PR3例,NR5例,总有效率73.68%。[结论]中药扶正解毒汤联合CAG方案治疗急性髓系白血病效果显著,值得推广使用。

[Objective]To observe the centralizer jiedu decoction combined the CAG scheme,the curative effect of treatment of acute myeloid leukemia.[Results]19 cases of hospitalized patients with acute myeloid leukemia to combine traditional Chinese and western medicine treatment,the CAG,cytarabine,10 mg/m2,1/12 h,subcutaneous injection. 1 ~ 14 d,o gentle than star,20 mg/times,1,3,5,7d,granulocyte colony stimulating factor(g-csf),200 mu G/m2,1/d,subcutaneous injection,0 ~ 13 d,white blood cell count is greater than 20 x 109 / L stopped. Chinese medicine treatment,the centralizer jiedu decoction,in order to help the vital qi,Baihuasheshecao,Huangshi,Shengdihuang,Jingtiansanqi each 20g,Taizishen,Tiandong, Maidong,Nanshashen,Beishashen,Danggui,Baishu,Tengligen,Banzhilian,Qingdai,Longkui every 10g, Dangshen 15g). 1/d boiling water 100 ml,oral sooner or later. Continuous treatment of 14d to 1 course of treatment. Observation of clinical symptoms and adverse reactions. Continuous treatment 1 treatment course, judge curative effect.[Results]CR11,PR3,NR5 example,the total effective rate was 73.68%. Traditional Chinese medicine(TCM).[Conclusion]The centralizer detoxification joint the CAG patients with acute myeloid leukemia effect is remarkable,is worth promoting.