丹蒌片联合西药治疗痰瘀互阻型冠心病心绞痛随机平行对照研究

Danlou Tablets Combined with Western Medicine in The Treatment of Phlegm And Blood Stasis Syndrome of Coronary Heart Disease and Angina Pectoris of Random Parallel Control

[目的]观察丹蒌片联合西药治疗痰瘀互阻型冠心病心绞痛疗效。[方法]使用随机平行对照方法,将120例门诊患者按随机数字表法分为两组。对照组60例阿司匹林,100mg/次,1次/d,口服;辛伐他汀,20mg/次,1次/d,口服;硝酸异山梨酯片,10mg/次,3次/d,口服。治疗组60例丹蒌片,1.5g/次,2次/d,口服。西药治疗同对照组。连续治疗28d为1疗程。观测临床症状、心绞痛发作情况,不良反应。治疗1疗程,判定疗效。[结果]治疗组显效29例,有效28例,无效3例,总有效率95.00%。对照组显效22例,有效28例,无效10例,总有效率83.33%。治疗组疗效优于对照组(P<0.05)。心绞痛发作情况两组均有改善(P<0.05),治疗组改善优于对照组(P<0.05)。[结论]丹蒌片联合西药治疗痰瘀互阻型冠心病心绞痛效果显著,值得推广。

[Objective]To observe the Danlou tablets combined with western medicine in the treatment of phlegm and blood stasis treating angina pectoris of coronary heart disease.[Methods]Using randomized controlled methods,120 patients were randomly divided into two groups. A control group of 60 patients with aspirin,100mg/,1 /d,oral + simvastatin,20mg/,1 /d,oral + isosorbide dinitrate tablets,10mg/,3 /d,oral.The treatment group of 60 cases of Danlou tablets,1.5g/,2 /d,oral. Western medicine treatment with the control group. 28d 1 treatment. Observation of clinical curative effect,angina,adverse reaction. 1 courses of treatment,the curative effect. 29 cases of group therapy[Results]28 cases were effective,3 cases ineffective,the total efficiency of 95.00%. The control group was 22 cases,effective 28 cases,invalid 10 cases,the total efficiency of 83.33%. The treatment group was better than control group(P< 0.05). Two groups of angina were improved(P< 0.05),the treatment group than the control group(P< 0.05).[Conclusion]Danlou tablets combined with western medicine in the treatment of phlegm and blood stasis syndrome of coronary heart disease and angina pectoris effect is significant,worthy of promotion.