利水方治疗高血压随机平行对照研究

Randomized Study of Traditional Chinese Medicine and Water Decoction in the Treatment of Hypertension

[目的]观察利水方治疗高血压疗效。[方法]使用随机平行对照方法,将100例住院患者按就诊顺序编号分为两组。对照组50例美多洛尔,100mg/次,1次/d,口服;沙坦药,80mg/次,1次/d,口服。在治疗期过程中根据患者血压对剂量耐受力进行适当调整。治疗组50例利水方(赤小豆、茯苓皮、夏枯草各13g,附子7g,桂枝、益母草各9g,杜仲10g,钩藤7g),1剂/d,水煎200mL,早晚口服。连续治疗15d为1疗程。观测临床症状、血压指标(SBP、DBP)、不良反应。连续治疗4疗程(60d),判定疗效。[结果]治疗组痊愈32例,显效13例,有效5例,无效0例,总有效率100.00%。对照组痊愈20例,显效15例,有效10例,无效5例,总有效率95.00%。治疗组疗效优于对照组(P<0.01)。血压指标(SBP、DBP)两组均有改善(P<0.05),治疗组改善优于对照组(P<0.05)。[结论]利水方治疗高血压效果显著,值得推广。

[Objective]To observe the traditional Chinese medicine and water decoction in the treatment of hypertension.[Methods]Using randomized controlled methods,100 patients were numbered according to the order of treatment were divided into two groups. A control group of 50 cases of metoprolol,100mg/,1 /d,oral;losartan drug,80mg/,1 /d,oral. Adjust the dosage according to the blood pressure in the treatment of patients with tolerance during the. The treatment group of 50 cases of TCM Lishui Decoction(Chixiaodou,Fulingpi,Xiakucao each 13g,Fuzi 7g,Guizhi,Yimucao each 9g,Duzhong 10g,Gouteng 7g),1 doses of /d,water simmer in water 200mL,sooner or later oral. Continuous treatment with 15d for 1 courses. Observation of clinical curative effect,blood pressure index(SBP,DBP),adverse reaction. Continuous treatment of 4 courses(60d),curative effect[.Results]The treatment group cured 32 cases,effective in 13 cases,effective 5 cases,invalid 0cases,the total efficiency of 100%. The control group cured 20 cases,effective in 15 cases,effective 10 cases,invalid 5 cases,the total efficiency of 95%. The treatment group was better than control group(P< 0.01).Blood pressure index(SBP,DBP)in two groups were improved(P< 0.05),the treatment group than the control group(P< 0.05).[Conclusion]Chinese water treatment of hypertensive effect is significant,worthy of promotion.